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  M. Mlle Mme
Nom Meltzer
Prénom Sara J.

Résumé du programme de recherche

Diabetic Pregnancies: Longitudinal Follow-up of Mother-Offspring Pairs: Women who had gestational diabetes are known to be at risk for developing type 2 DM and there is evidence that diabetes during pregnancy may have long-term consequences for an offspring’s health status later in life. We propose to conduct a longitudinal follow-up evaluation of mother-daughter pairs recruited from consecutive birth years (1989-1991) representing children reaching 14-15 years of age as of 2004. All women who had GDM or type 2 DM during pregnancy, as documented by the Royal Victoria Hospital, and a pregnancy that resulted in a live female singleton birth will be eligible for study participation. A comparison group of similarly aged mothers and their female infants with no documented pregnancy-related complication will be recruited from the same birth cohorts, utilizing Royal Victoria records and the McGill Obstetrics and Neonatal Database (MOND). There are no specific hypothesis in the study, more an assessment of : - prevalence of glucose abnormalities 14 years later in the mothers - evaluation of anthropomorphic, behavioural and metabolic risk factors of daughters (control vs GDM) - compare mother-daughter risk factors - determine if mothers’ risk factors can predict daughters’ risks - determine antecedents and correlates of teen obesity. It is hoped that the information obtained in this study may determine the role of diabetes in the increasing prevalence of both teenage obesity and type 2 DM. June/ 2003 for 3 years. Long-term psychological development consequences of maternal hypoglycemia in mothers with type 1 DM: co-investigator at one of 3 centres, Calgary (Dr. D. Pacaud, principal investigator; Toronto, Dr. Amir Hanna and Montreal, myself). Initial year funded by CIHR. Remaining study re-funded by the Alberta Heritage Foundation for June, 2004 for 3 years.
Domaine(s) couverts par la recherche
1 Recherche clinique
2 Systèmes et services de santé
3 Facteurs sociaux, culturels et autres du développement des enfants de 0-5 ans
Mots clés
diabète sucré gestationnel / diabète sucré de grossesse
nutrition
épidémiologie
lipides
surveillance sanitaire
hypoglycémie maternelle
Publications CDA 2003 Clinical Practice Guidelines, Meltzer SJ, Ryan EA, Feig D, Thompson D, Snyder J Pre-Existing Diabetes in Pregnancy – preparation of initial draft, Can. J. Diab. 2003 S94-S98.
CDA 2003 Clinical Practice Guidelines, Meltzer SJ, , Feig D, Ryan EA ,Thompson D, Snyder J Gestational Diabetes Mellitus – preparation of initial draft, Can. J. Diab. 2003 S94-S98.
Meltzer, S J Editorial: making the case for Euglycemia in women with Gestational Diabetes Mellitus. Can. J. Diab. 2003 vol. 27, No. 4(Dec), p 417-418.
 
Coordonnées  
Titre Professeure agrégée
Département / Faculté Obstétrique et gynécologie / Médecine
Institution McGill University
Adresse M9.22, MUHC-Royal Victoria Hospital
Ville Montreal
Province Québec
Code postal H3A 1A1
Numéro de téléphone (514) 9341934 # 34663
Numéro de télécopieur (514) 9820825
Courrier électronique sara.meltzer@muhc.mcgill.ca
 
Qualifications académiques (université, département, diplôme, année d'obtention) MD, University of Alberta 1972 FRCPC Internal Medicine 1978 ABIM, Internal Medicine 1978 Certificate of Specialite Province du Quebec (Endocrinology) 1978
Sources de financement ACD - Association canadienne du diabète, IRSC - Instituts de recherche en santé du Canada, Pfizer
Langues de travail anglais, français
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